Welcome to the COINSTAC Vaults!
Vault contains sample COINSTAC data located on the server, made available to COINSTAC users at all times. Vaults help overcome the challenge of having everyone online at the same time to collaborate in COINSTAC. You can use these datasets and run various computations in COINSTAC to see the results. Once the Vault data is added, you can run a regression on the Vault data using all or covariates of your choice made available in the vault, and importantly you can also connect the Vault with other COINSTAC nodes to increase the sample size without centrally pooling the data. This we hope provides an initial example of the potential of using COINSTAC for big data collaborative research involving sensitive data that can’t be shared across sites.
Vaults available in COINSTAC
TReNDS VBM COBRE
This vault contains data from 152 subjects, approximately half controls and half individuals with chronic schizophrenia, collected as part of the Mind Research Network COBRE study . The vault includes gray matter segmentation data from an SPM VBM preprocessing pipeline. In addition, we have demographic, symptom, and cognitive variables to select from in building a desired model.
TReNDS FreeSurfer COBRE
This vault contains data from 152 subjects, approximately half controls and half individuals with chronic schizophrenia, collected as part of the Mind Research Network COBRE study (https://www.nature.com/articles/sdata2017181). The vault includes cortical and sub-cortical volumetric and surface based measurements from two FreeSurfer atlases, Desikan-Killiany and Destrieux. In addition, we include demographic, symptom, and cognitive variables which can be used to build a desired model.
Child Mind Institute (CMI) FreeSurfer Healthy Brain Network
This vault contains data from 885 children and adolescents (ages 5 – 21), collected as part of the Healthy Brain Network study (REF). The vault includes brain volumes from Desikan Killiany FreeSurfer atlas. In addition, we have demographic, cognitive, and substance use variables to select from when building a desired model.
We are planning many more Vaults going forward! We will initially release vaults highlighting various existing pipelines. Two more that are coming soon are listed below:
Child Mind Institute (CMI) VBM VAULT
TReNDS NeuroMark Group-ICA COBRE VAULT
Check out this demo of how to run regression on Freesurfer volumes on the CMI Vault.
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